Profile

Nasim Maleki

Harvard Medical School

Contact Details

Harvard Medical School

Bio / CV / Publications

 Bio:

I am an Assistant Professor of Psychiatry at Harvard Medical School who has a longstanding interest in identifying biomarkers for the onset and evolution of brain disorders with a specific focus on migraine disease and pain disorders. I also have extensive experience in developing and applying advanced multimodal neuroimaging techniques to study brain structure, function, and chemistry. I collaborate with multiple disciplines and perform cross-modality/interdisciplinary studies to understand how changes in the brain mediate the onset and evolution of brain disorders, and how such knowledge can ultimately inform development of customized and personalized treatments for patients.

 

Publications:

  1. 1. Newman-Norlund RD, Rorden C, Maleki N, Patel M, Cheng B, Androulakis XM. Cortical and subcortical changes following sphenopalatine ganglion blocks in chronic migraine with medication overuse headache: a preliminary longitudinal study. Womens Midlife Health. 2020; 6:7. PMID: 32774872.

    2. Tu Y, Zeng F, Lan L, Li Z, Maleki N, Liu B, Chen J, Wang C, Park J, Lang C, Yujie G, Liu M, Fu Z, Zhang Z, Liang F, Kong J. An fMRI-based neural marker for migraine without aura. Neurology. 2020 02 18; 94(7):e741-e751. PMID: 31964691.

    3. Maleki N, Androulakis XM. Is There Any MRI Pattern That Discriminates Female From Male Migraine Patients? Front Neurol. 2019; 10:961. PMID: 31551917.

    4. Maleki N, Tahaney K, Thompson BL, Oscar-Berman M. At the intersection of alcohol use disorder and chronic pain. Neuropsychology. 2019 Sep; 33(6):795-807. PMID: 31448947.

    5. Tu Y, Fu Z, Maleki N. When does the youthfulness of the female brain emerge? Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10632-10633. PMID: 31138714.

    6. Tu Y, Fu Z, Zeng F, Maleki N, Lan L, Li Z, Park J, Wilson G, Gao Y, Liu M, Calhoun V, Liang F, Kong J. Abnormal thalamocortical network dynamics in migraine. Neurology. 2019 06 04; 92(23):e2706-e2716. PMID: 31076535.

    7. Maleki N, Cheng YC, Tu Y, Locascio JJ. Longitudinal course of vasomotor symptoms in perimenopausal migraineurs. Ann Neurol. 2019 06; 85(6):865-874. PMID: 30937949.

    8. Sawyer KS, Maleki N, Urban T, Marinkovic K, Karson S, Ruiz SM, Harris GJ, Oscar-Berman M. Alcoholism gender differences in brain responsivity to emotional stimuli. Elife. 2019 04 30; 8. PMID: 31038125.

    9. Androulakis XM, Krebs KA, Jenkins C, Maleki N, Finkel AG, Rorden C, Newman R. Central Executive and Default Mode Network Intranet work Functional Connectivity Patterns in Chronic Migraine. J Neurol Disord. 2018; 6(5). PMID: 30574520.

    10. Bernstein C, Shifren J, Maleki N. Need for Migraine/Perimenopausal Research. Headache. 2018 11; 58(10):1670-1674. PMID: 30194719.

    11. Schroeder RA, Brandes J, Buse DC, Calhoun A, Eikermann-Haerter K, Golden K, Halker R, Kempner J, Maleki N, Moriarty M, Pavlovic J, Shapiro RE, Starling A, Young WB, Nebel RA. Sex and Gender Differences in Migraine-Evaluating Knowledge Gaps. J Womens Health (Larchmt). 2018 08; 27(8):965-973. PMID: 30129895.

    12. Sawyer KS, Maleki N, Papadimitriou G, Makris N, Oscar-Berman M, Harris GJ. Cerebral white matter sex dimorphism in alcoholism: a diffusion tensor imaging study. Neuropsychopharmacology. 2018 08; 43(9):1876-1883. PMID: 29795404.

    13. Curie A, Friocourt G, des Portes V, Roy A, Nazir T, Brun A, Cheylus A, Marcorelles P, Retzepi K, Maleki N, Bussy G, Paulignan Y, Reboul A, Ibarrola D, Kong J, Hadjikhani N, Laquerrière A, Gollub RL. Basal ganglia involvement in ARX patients: The reason for ARX patients very specific grasping? Neuroimage Clin. 2018; 19:454-465. PMID: 29984154.

    14. Gollub RL, Kirsch I, Maleki N, Wasan AD, Edwards RR, Tu Y, Kaptchuk TJ, Kong J. A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients With Knee Osteoarthritis. J Pain. 2018 05; 19(5):515-527. PMID: 29325883.

    15. Blokland GAM, Del Re EC, Mesholam-Gately RI, Jovicich J, Trampush JW, Keshavan MS, DeLisi LE, Walters JTR, Turner JA, Malhotra AK, Lencz T, Shenton ME, Voineskos AN, Rujescu D, Giegling I, Kahn RS, Roffman JL, Holt DJ, Ehrlich S, Kikinis Z, Dazzan P, Murray RM, Di Forti M, Lee J, Sim K, Lam M, Wolthusen RPF, de Zwarte SMC, Walton E, Cosgrove D, Kelly S, Maleki N, Osiecki L, Picchioni MM, Bramon E, Russo M, David AS, Mondelli V, Reinders AATS, Falcone MA, Hartmann AM, Konte B, Morris DW, Gill M, Corvin AP, Cahn W, Ho NF, Liu JJ, Keefe RSE, Gollub RL, Manoach DS, Calhoun VD, Schulz SC, Sponheim SR, Goff DC, Buka SL, Cherkerzian S, Thermenos HW, Kubicki M, Nestor PG, Dickie EW, Vassos E, Ciufolini S, Reis Marques T, Crossley NA, Purcell SM, Smoller JW, van Haren NEM, Toulopoulou T, Donohoe G, Goldstein JM, Seidman LJ, McCarley RW, Petryshen TL. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. Schizophr Res. 2018 05; 195:306-317. PMID: 28982554.

    16. Androulakis XM, Krebs K, Peterlin BL, Zhang T, Maleki N, Sen S, Rorden C, Herath P. Modulation of intrinsic resting-state fMRI networks in women with chronic migraine. Neurology. 2017 Jul 11; 89(2):163-169. PMID: 28615426.

    17. Pavlovic JM, Akcali D, Bolay H, Bernstein C, Maleki N. Sex-related influences in migraine. J Neurosci Res. 2017 01 02; 95(1-2):587-593. PMID: 27870430.

    18. Maleki N, Kurth T, Field AE. Age at menarche and risk of developing migraine or non-migraine headaches by young adulthood: A prospective cohort study. Cephalalgia. 2017 Nov; 37(13):1257-1263. PMID: 27919016.

    19. Maleki N, Gollub RL. What Have We Learned From Brain Functional Connectivity Studies in Migraine Headache? Headache. 2016 Mar; 56(3):453-61. PMID: 26924634.

    20. Maleki N, Bernstein C, Napadow V, Field A. Migraine and Puberty: Potential Susceptible Brain Sites. Semin Pediatr Neurol. 2016 Feb; 23(1):53-9. PMID: 27017023.

    21. Maleki N, Barmettler G, Moulton EA, Scrivani S, Veggeberg R, Spierings EL, Burstein R, Becerra L, Borsook D. Female migraineurs show lack of insular thinning with age. Pain. 2015 Jul; 156(7):1232-9. PMID: 25775358.

    22. Barmettler G, Brawn J, Maleki N, Scrivani S, Burstein R, Becerra L, Borsook D. A new electronic diary tool for mapping and tracking spatial and temporal head pain patterns in migraine. Cephalalgia. 2015 Apr; 35(5):417-25. PMID: 25143550.

    23. Maleki N, Brawn J, Barmettler G, Borsook D, Becerra L. Pain response measured with arterial spin labeling. NMR Biomed. 2013 Jun; 26(6):664-73. PMID: 23319440.

    24. Linnman C, Maleki N, Becerra L, Borsook D. Migraine tweets - what can online behavior tell us about disease? Cephalalgia. 2013 Jan; 33(1):68-9. PMID: 23136208.

    25. Maleki N, Becerra L, Borsook D. Migraine: maladaptive brain responses to stress. Headache. 2012 Oct; 52 Suppl 2:102-6. PMID: 23030541.

    26. Maleki N, Linnman C, Brawn J, Burstein R, Becerra L, Borsook D. Her versus his migraine: multiple sex differences in brain function and structure. Brain. 2012 Aug; 135(Pt 8):2546-59. PMID: 22843414.

    27. Maleki N, Becerra L, Brawn J, McEwen B, Burstein R, Borsook D. Common hippocampal structural and functional changes in migraine. Brain Struct Funct. 2013 Jul; 218(4):903-12. PMID: 22760159.

    28. Maleki N, Becerra L, Brawn J, Bigal M, Burstein R, Borsook D. Concurrent functional and structural cortical alterations in migraine. Cephalalgia. 2012 Jun; 32(8):607-20. PMID: 22623760.

    29. Toledo E, Lebel A, Becerra L, Minster A, Linnman C, Maleki N, Dodick DW, Borsook D. The young brain and concussion: imaging as a biomarker for diagnosis and prognosis. Neurosci Biobehav Rev. 2012 Jul; 36(6):1510-31. PMID: 22476089.

    30. Shelton L, Pendse G, Maleki N, Moulton EA, Lebel A, Becerra L, Borsook D. Mapping pain activation and connectivity of the human habenula. J Neurophysiol. 2012 May; 107(10):2633-48. PMID: 22323632.

    31. Borsook D, Maleki N, Becerra L, McEwen B. Understanding migraine through the lens of maladaptive stress responses: a model disease of allostatic load. Neuron. 2012 Jan 26; 73(2):219-34. PMID: 22284178.

    32. Maleki N, Dai W, Alsop DC. Optimization of background suppression for arterial spin labeling perfusion imaging. MAGMA. 2012 Apr; 25(2):127-33. PMID: 22009131.

    33. Maleki N, Becerra L, Nutile L, Pendse G, Brawn J, Bigal M, Burstein R, Borsook D. Migraine attacks the Basal Ganglia. Mol Pain. 2011 Sep 21; 7:71. PMID: 21936901.

    34. Maleki N, Alsop DC, Dai W, Hudson C, Han JS, Fisher J, Mikulis D. The effect of hypercarbia and hyperoxia on the total blood flow to the retina as assessed by magnetic resonance imaging. Invest Ophthalmol Vis Sci. 2011 Aug 29; 52(9):6867-74. PMID: 21447683.

    35. Maleki N, Becerra L, Upadhyay J, Burstein R, Borsook D. Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia. Hum Brain Mapp. 2012 Jan; 33(1):75-88. PMID: 21337474.

    36. Maleki N, Dai W, Alsop DC. Blood flow quantification of the human retina with MRI. NMR Biomed. 2011 Jan; 24(1):104-11. PMID: 20862658.

    37. Moulton EA, Becerra L, Maleki N, Pendse G, Tully S, Hargreaves R, Burstein R, Borsook D. Painful heat reveals hyperexcitability of the temporal pole in interictal and ictal migraine States. Cereb Cortex. 2011 Feb; 21(2):435-48. PMID: 20562317.

    38. Upadhyay J, Maleki N, Potter J, Elman I, Rudrauf D, Knudsen J, Wallin D, Pendse G, McDonald L, Griffin M, Anderson J, Nutile L, Renshaw P, Weiss R, Becerra L, Borsook D. Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. Brain. 2010 Jul; 133(Pt 7):2098-114. PMID: 20558415.